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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1985374Generated: October 26, 2026

1-Isocyanato-4-methoxybenzene → Dimethyl 2-[4-ethoxy-3-({[(4-methoxyanilino)carbonyl]oxy}methyl)benzyl]malonate

https://huagongshe.com/reaction/1985374

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Isocyanato-4-methoxybenzeneHCID 79443—
ReactantDimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]malonateHCID 22926717—
ProductDimethyl 2-[4-ethoxy-3-({[(4-methoxyanilino)carbonyl]oxy}methyl)benzyl]malonateHCID 57719745—

Reaction Steps

Using dimethyl 2-[4-ethoxy-3-(hydroxymethyl)benzyl]malonate and 4-methoxyphenylisocyanate, the title compound was obtained in the same manner as described in Example 192b).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07544835B2
Source datasetuspto-grants-2009_06
ORD IDord-ccc771b8b6bb4ace9cd81b20b02f3d6a
Source noteuspto-grants-2009_06