HCID 57719660, compound → HCID 57719575, compound

HRID 1985393Notes

Reaction equation

HRID 1985393 reaction equation
C(OC([NH:8][C:9]1[N:14]=[CH:13][C:12]([CH2:15][O:16][C:17]([NH:19][CH2:20][C:21]2[CH:22]=[C:23]([CH2:27][C@H:28]([O:32][CH:33]([CH3:35])[CH3:34])[C:29]([OH:31])=[O:30])[CH:24]=[CH:25][CH:26]=2)=[O:18])=[CH:11][CH:10]=1)=O)(C)(C)C>FC(F)(F)C(O)=O>[NH2:8][C:9]1[N:14]=[CH:13][C:12]([CH2:15][O:16][C:17]([NH:19][CH2:20][C:21]2[CH:22]=[C:23]([CH2:27][C@H:28]([O:32][CH:33]([CH3:35])[CH3:34])[C:29]([OH:31])=[O:30])[CH:24]=[CH:25][CH:26]=2)=[O:18])=[CH:11][CH:10]=1

Participants

3

Reactant 1

HCID 57719660HCID 57719660, compound

Product 1

HCID 57719575HCID 57719575, compound

Reagents, catalysts & solvents 1

HCID 6422Trifluoroacetic acidSolvent

Procedure

3-{3-[(6-t-Butoxycarbonylaminopyridin-3-ylmethoxycarbonylamino)methyl]phenyl}-2(S)-isopropoxypropanoic acid was dissolved in trifluoroacetic acid, and the mixture was concentrated. The residue was purified by reverse-phase high performance liquid chromatography, to give the title compound.

Workup

  1. concentrationthe mixture was concentrated
  2. customThe residue was purified by reverse-phase high performance liquid chromatography

Sources & evidence

ORD record
ord-a8632745d2934042a1d6c7735442f735
Source dataset
uspto-grants-2009_06
Patent number
US07544835B2

Reaction notes

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