Hydrazine hydrate (1:1) → 3-(2,2-Dimethyl-propyl)-6,6-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridazine

HRID 1985604Notes

Reaction equation

HRID 1985604 reaction equation
[CH3:1][C:2]1([CH3:9])[CH2:6][C:5](=O)[C:4](=O)[CH2:3]1.COP([CH2:16][C:17](=O)[CH2:18][C:19]([CH3:22])([CH3:21])[CH3:20])(=O)OC.O.[NH2:25][NH2:26]>>[CH3:20][C:19]([CH3:22])([CH3:21])[CH2:18][C:17]1[N:26]=[N:25][C:4]2[CH2:3][C:2]([CH3:9])([CH3:1])[CH2:6][C:5]=2[CH:16]=1

Participants

4

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 142896544,4-Dimethylcyclopentane-1,2-dioneHCID 25112585(4,4-Dimethyl-2-oxo-pentyl)-phosphonic acid dimethyl ester

Product 1

HCID 247726613-(2,2-Dimethyl-propyl)-6,6-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridazine

Procedure

off-white solid. MS (ESI): 219.3 (MH+). Prepared from 4,4-dimethyl-cyclopentane-1,2-dione, (4,4-dimethyl-2-oxo-pentyl)-phosphonic acid dimethyl ester, hydrazine monohydrate.

Sources & evidence

ORD record
ord-0a1e6f9ea28c4b35822c6ae014d9d0f3
Source dataset
uspto-grants-2009_06
Patent number
US07547697B2

Reaction notes

Loading…