Hydrazine hydrate (1:1) → 3-Cyclopropylmethyl-6,6-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridazine

HRID 1985612Notes

Reaction equation

HRID 1985612 reaction equation
[CH3:1][C:2]1([CH3:9])[CH2:6][C:5](=O)[C:4](=O)[CH2:3]1.COP([CH2:16][C:17](=O)[CH2:18][CH:19]1[CH2:21][CH2:20]1)(=O)OC.O.[NH2:24][NH2:25]>>[CH:19]1([CH2:18][C:17]2[N:25]=[N:24][C:4]3[CH2:3][C:2]([CH3:9])([CH3:1])[CH2:6][C:5]=3[CH:16]=2)[CH2:21][CH2:20]1

Participants

4

Reactant 3

HCID 24654Hydrazine hydrate (1:1)HCID 142896544,4-Dimethylcyclopentane-1,2-dioneHCID 86617460(3-Cyclopropyl-2-oxo-propyl)-phosphonic acid dimethyl ester

Product 1

HCID 688438153-Cyclopropylmethyl-6,6-dimethyl-6,7-dihydro-5H-cyclopenta[c]pyridazine

Procedure

Prepared from 4,4-dimethyl-cyclopentane-1,2-dione, (3-cyclopropyl-2-oxo-propyl)-phosphonic acid dimethyl ester, hydrazine monohydrate.

Sources & evidence

ORD record
ord-0d0612f7cff74d73bc68da7135bcf0a5
Source dataset
uspto-grants-2009_06
Patent number
US07547697B2

Reaction notes

Loading…