tert-Butyl acrylate → HCID 57720149, compound

Participants

Reaction Conditions

Reaction Steps

To the solution of (2-amino-ethylamino)-acetic acid tert-butyl ester (1.0 mL, 6.32 mmol) in i-PrOH (50 mL) was added acrylic acid tert-butyl ester (309.1 μL, 2.11 mmol). The suspension was heated for 48 hours at 60° C. The solvent was evaporated and product was purificated by column chromatography (DCM-MeOH—NH3=90:3:0.5) yielded the title product as colorless oil (0.45 mg).

Provenance & Evidence