1-(Triphenylmethyl)pyridin-1-ium tetrafluoridoborate(1-) → HCID 69063830, compound

HRID 1985731Notes

Reaction equation

HRID 1985731 reaction equation
[C:1]([O:5][C:6]([N:8]1[CH2:20][C@@H:19]([CH3:21])[N:18]2[C@H:10]([CH2:11][C:12]3[C:17]2=[N:16][C:15]([CH2:22][SH:23])=[C:14]([Br:24])[CH:13]=3)[CH2:9]1)=[O:7])([CH3:4])([CH3:3])[CH3:2].F[B-](F)(F)F.[C:30]([N+]1C=CC=CC=1)([C:43]1[CH:48]=[CH:47][CH:46]=[CH:45][CH:44]=1)([C:37]1[CH:42]=[CH:41][CH:40]=[CH:39][CH:38]=1)[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1>ClCCl>[C:1]([O:5][C:6]([N:8]1[CH2:20][C@@H:19]([CH3:21])[N:18]2[C@H:10]([CH2:11][C:12]3[C:17]2=[N:16][C:15]([CH2:22][S:23][C:30]([C:31]2[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=2)([C:43]2[CH:44]=[CH:45][CH:46]=[CH:47][CH:48]=2)[C:37]2[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=2)=[C:14]([Br:24])[CH:13]=3)[CH2:9]1)=[O:7])([CH3:2])([CH3:3])[CH3:4]

Participants

4

Reactant 2

HCID 99094121-(Triphenylmethyl)pyridin-1-ium tetrafluoridoborate(1-)HCID 86608947HCID 86608947, compound

Product 1

HCID 69063830HCID 69063830, compoundYield 98.4%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

To a solution of 0.25 g of the product of step 1 in 5 ml dichloromethane was added 0.25 g tritylpyridinium tetrafluoroborate at room temperature and the mixture was stirred at this temperature for 2 h. The reaction mixture was purified by chromatography on silica gel with dichlorometha:ethyl aceate=19:1 to yield 0.39 g of the title compound as colorless foam (MS: 656.3 and 658,4 (M+H+)).

Workup

  1. customThe reaction mixture was purified by chromatography on silica gel with dichlorometha

Sources & evidence

ORD record
ord-33f84ec3f730424ea2ae1f6ccd9b8071
Source dataset
uspto-grants-2009_06
Patent number
US07547699B2

Reaction notes

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