反应详情

The mixture of N-cyclopropyl-4-fluoro-3-nitrobenzenesulfonamide (520 mg, 2 mmol) and Pd/C (10%, 100 mg) in EtOH was hydrogenated (1 atm) overnight. The mixture was filtered through a short pad of celite and concentrated in vacuo to afford N-cyclopropyl-4-fluoro-3-aminobenzenesulfonamide (440 mg, 95% ) as an ivory solid. LC/MS; (M+H)+=231.

1. custom(1 atm) overnight
2. filtrationThe mixture was filtered through a short pad of celite
3. concentrationconcentrated in vacuo