反应详情

2-Chloro-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1H-benzimidazole (12.3 g) was dissolved in methanol (150 mL). To the mixture was added 28% sodium methoxide-methanol solution (1 mL), and the mixture was stirred for 1 hour. The reaction mixture was concentrated under reduced pressure to give the title compound (8.5 g).

1. concentrationThe reaction mixture was concentrated under reduced pressure