HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-1-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-1H-benzimidazole → 22423-42-3
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-1-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-1H-benzimidazole | HCID 21817393 | — |
| Reactant | Sodium methanolate methanol | HCID 23694274 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 22423-42-3 | HCID 469422 | 99.7% |
Reaction Steps
2-Chloro-1-(2,3,5-tri-O-acetyl-β-D-ribofuranosyl)-1H-benzimidazole (12.3 g) was dissolved in methanol (150 mL). To the mixture was added 28% sodium methoxide-methanol solution (1 mL), and the mixture was stirred for 1 hour. The reaction mixture was concentrated under reduced pressure to give the title compound (8.5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547680B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-4ef16211375a4b3f95d3e6dc4a1f36cd |
| Source note | uspto-grants-2009_06 |