反应详情

温度

60 °C

Lithium aluminum hydride (0.20 g) was suspended in tetrahydrofuran (15 mL). To the mixture was added 3-(4-acetoxy-butylsulfanyl)benzonitrile (0.75 g) under ice-cooling. The mixture was stirred at 60° C. for 2 hours, and the mixture was cooled under ice-cooling. To the reaction mixture were added dropwise ethanol and water successively, and then added diethyl ether. To the reaction mixture was added anhydrous sodium sulfate, and the insoluble material was removed by filtration. The filtrate was concentrated under reduced pressure to give the title compound (0.22 g).

1. temperaturecooling
2. temperaturethe mixture was cooled under ice-
3. temperaturecooling
4. customthe insoluble material was removed by filtration
5. concentrationThe filtrate was concentrated under reduced pressure