Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4,4,4-Trifluoro-2-(2,2,2-trifluoroethyl)but-2-enoic acid ethyl ester → 4,4,4-Trifluoro-2-(2,2,2-trifluoroethyl)-butyric acid ethyl ester
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4,4,4-Trifluoro-2-(2,2,2-trifluoroethyl)but-2-enoic acid ethyl ester | HCID 74410056 | — |
| 촉매 | Palladium | HCID 23938 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 4,4,4-Trifluoro-2-(2,2,2-trifluoroethyl)-butyric acid ethyl ester | HCID 44541425 | 99.1% |
반응 단계
4,4,4-Trifluoro-2-(2,2,2-trifluoroethyl)-but-2-enoic acid ethyl ester (5.0 g, 20.0 mmol) in THF (20 mL) was treated with Pd/C (2.5 g, 5%), and H2 (1 atm.) at 25° C. for 17 h. The reaction mixture was filtered through a pad of the Celite® reagent, rinsed with Et2O (50 mL) and the filtrate was distilled to remove Et2O and THF to afford the product as colorless liquid (5.0 g, 99%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07547725B2 |
| 출처 데이터셋 | uspto-grants-2009_06 |
| ORD ID | ord-88c0e1a63db3412d8a3e3a4847a76e0d |
| 출처 메모 | uspto-grants-2009_06 |