Hydrochloric Acid → HCID 67046027, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 4-(4-chloro-3-trifluoromethyl-phenoxy)-1,2,2,6,6-pentamethyl-piperidine (1.28 g, 4.26 mmol), toluene (50 ml) and diethylazodicarboxylate (2.0 ml, 12.8 mmol) was heated at 110° C. for 8 h. Hydrochloric acid (20 ml, 2 M) was added at reflux for 2 h. The mixture was cooled on ice. The hydrochloric acid salt precipitated and was isolated by filtration. Yield 1.2 g (87%). Mp 222° C.

Provenance & Evidence