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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1986163Generated: November 1, 2026

Tert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylate → tert-butyl 5-(2-aminoethyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylate

https://huagongshe.com/reaction/1986163

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-butyl octahydropyrrolo(3,4-c)pyrrole-2-carboxylateHCID 4142526—
Reactant1-tert-Butyloxycarbonyl-4-(3-aminopropyl)piperazineHCID 17750945—
Producttert-butyl 5-(2-aminoethyl)hexahydropyrrolo[3,4-c]pyrrole-2(1H)-carboxylateHCID 68857810—

Reaction Steps

Using the method of 4-(3-aminopropyl)-piperazine-1-carboxylic acid tert-butyl ester, the title compound is synthesized from hexahydropyrrolo[3,4-c]pyrrole-2-carboxylic acid tert-butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07547691B2
Source datasetuspto-grants-2009_06
ORD IDord-a426c7dbe5994a5aa92b5f4d7361a05f
Source noteuspto-grants-2009_06