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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1986212Generated: October 30, 2026

1-N-Boc-4-Piperidinecarboxylic acid methyl ester → 1-Tert-butyl 4-methyl 4-ethylpiperidine-1,4-dicarboxylate

https://huagongshe.com/reaction/1986212

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-N-Boc-4-Piperidinecarboxylic acid methyl esterHCID 392870—
Reactant1-tert-Butyl 4-methyl 4-methylpiperidine-1,4-dicarboxylateHCID 46318388—
Product1-Tert-butyl 4-methyl 4-ethylpiperidine-1,4-dicarboxylateHCID 46318389—

Reaction Steps

Using the method of 4-methylpiperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-methyl ester, the title compound is synthesized from piperidine-1,4-dicarboxylic acid 1-tert-butyl ester 4-methyl ester and isolated as a tan oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07547691B2
Source datasetuspto-grants-2009_06
ORD IDord-11576c155f1442ff8bbe02c54f39acbe
Source noteuspto-grants-2009_06