HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-{5-Chloro-2-[3-(2,6-cis-dimethylpiperazin-1-yl)-propylamino]-pyrimidin-4-yl}-benzo[b]thiophene-4-carboxylic acid cyclopropylamide → HCID 68857773, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-{5-Chloro-2-[3-(2,6-cis-dimethylpiperazin-1-yl)-propylamino]-pyrimidin-4-yl}-benzo[b]thiophene-4-carboxylic acid cyclopropylamide | HCID 68855988 | — |
| Reactant | 3-(4-Benzhydryl-2,6-cis-dimethyl-piperazin-1-yl)-propylamine | HCID 68857348 | — |
| Reactant | 2-(2-Chloro-5-methylpyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamide | HCID 86625377 | — |
| Product | HCID 68857773 | HCID 68857773 | — |
Reaction Steps
Using the method of 2-{5-chloro-2-[3-(2,6-cis-dimethylpiperazin-1-yl)-propylamino]-pyrimidin-4-yl}-benzo[b]thiophene-4-carboxylic acid cyclopropylamide, the title compound is synthesized from 2-(2-chloro-5-methylpyrimidin-4-yl)-benzo[b]thiophene-4-carboxylic acid cyclopropylamide and 3-(4-benzhydryl-2,6-cis-dimethylpiperazin-1-yl)-propylamine as a yellow solid. ES+(m/z) 479 [M+H].
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07547691B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-1789426a2b1d42528891b316deac3bf2 |
| Source note | uspto-grants-2009_06 |