Acetic Acid → 3-(4-Chloro-2-fluoro-5-hydroxyphenyl)-1-methyl-6-trifluoromethyl-2-oxo-1,2-dihydropyrazine
Reaction equation
[BrH:23].[CH3:25][C:26](=[O:27])[OH:28].[Cl:1][c:2]1[cH:3][c:4]([F:22])[c:5](-[c:10]2[c:11](=[O:21])[n:12]([CH3:20])[c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][n:15]2)[cH:6][c:7]1[O:8][CH3:9].[OH2:24]>>[Cl:1][c:2]1[cH:3][c:4]([F:22])[c:5](-[c:10]2[c:11](=[O:21])[n:12]([CH3:20])[c:13]([C:16]([F:17])([F:18])[F:19])[cH:14][n:15]2)[cH:6][c:7]1[OH:8]Participants
5
Sources & evidence
- ORD record
- ord-705421aaffc141b4aa0df8f1706bdf3c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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