Potassium Carbonate → HCID 44140827, compound

HRID 1986520Notes

Reaction equation

HRID 1986520 reaction equation
C([O:4][C@H:5]1[CH:22]=[CH:21][C@@:20]2([CH3:23])[C:7](=[CH:8][CH2:9][C@@H:10]3[C@@H:19]2[CH2:18][CH2:17][C@@:15]2([CH3:16])[C@H:11]3[CH2:12][CH2:13][C:14]2=[O:24])[CH2:6]1)(=O)C.C(=O)([O-])[O-].[K+].[K+]>CO.O>[OH:4][C@H:5]1[CH:22]=[CH:21][C@@:20]2([CH3:23])[C:7](=[CH:8][CH2:9][C@@H:10]3[C@@H:19]2[CH2:18][CH2:17][C@@:15]2([CH3:16])[C@H:11]3[CH2:12][CH2:13][C:14]2=[O:24])[CH2:6]1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 11198244HCID 11198244, compound

Product 1

HCID 44140827HCID 44140827, compound

Reagents, catalysts & solvents 1

HCID 22242641Methanol--water (1/1)Solvent

Procedure

A mixture of compound 6 (0.25 g) and potassium carbonate (0.3 g) in methanol-water (15 ml, 9:1) was stirred at room temperature for 8 hr. Solution was concentrated diluted with cold water, cooled and the precipitated solid was filtered, and crystallized from methanol. White solid, mp. 138-40° C.

Workup

  1. concentrationSolution was concentrated
  2. additiondiluted with cold water
  3. temperaturecooled
  4. filtrationthe precipitated solid was filtered
  5. customcrystallized from methanol

Sources & evidence

ORD record
ord-88d7d293dc5d49b0b00e4a5cb314e001
Source dataset
uspto-grants-2009_06
Patent number
US07550450B2

Reaction notes

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