N,N-Dimethylethylenediamine → HCID 178483756, compound

HRID 1986557Notes

Reaction equation

HRID 1986557 reaction equation
[CH:1]1[C:11]2[C:10](=O)[NH:9][C:8]3[CH:13]=[CH:14][CH:15]=[CH:16][C:7]=3[NH:6][C:5]=2[CH:4]=[CH:3][CH:2]=1.[CH3:17][N:18]([CH3:22])[CH2:19][CH2:20][NH2:21]>>[CH:1]1[C:11]2[C:10]([NH:21][CH2:20][CH2:19][N:18]([CH3:22])[CH3:17])=[N:9][C:8]3[CH:13]=[CH:14][CH:15]=[CH:16][C:7]=3[NH:6][C:5]=2[CH:4]=[CH:3][CH:2]=1

Participants

3

Reactant 2

HCID 66053N,N-DimethylethylenediamineHCID 2013275,10-Dihydro-11H-dibenzo(b,e)(1,4)diazepin-11-one

Product 1

HCID 178483756HCID 178483756, compoundYield 27.1%

Procedure

5,10-Dihydro-dibenzo[b,e][1,4]diazepine-11-one (160FE15A) (21 mg, 0.1 mmol) and N,N-dimethylethylenediamine (88 mg, 1.0 mmol) were reacted according to GP4 to give 7.6 mg of the title compound (160FE20B). MS (ESI) 281 (MH+). Purity for MH+ (UV/MS) 100/100.

Sources & evidence

ORD record
ord-f75100f72a004a18bded03d15e7f3471
Source dataset
uspto-grants-2009_06
Patent number
US07550454B2

Reaction notes

Loading…