2,5-Dimethylpiperazine, trans- → HCID 136360191, compound

HRID 1986559Notes

Reaction equation

HRID 1986559 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[C:8](=O)[NH:7][C:6]=2[CH:17]=1.[CH3:18][C@H:19]1[CH2:24][NH:23][C@H:22]([CH3:25])[CH2:21][NH:20]1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[NH:11][C:10]3[CH:12]=[CH:13][CH:14]=[CH:15][C:9]=3[C:8]([N:20]3[CH2:21][C@@H:22]([CH3:25])[NH:23][CH2:24][C@@H:19]3[CH3:18])=[N:7][C:6]=2[CH:17]=1

Participants

3

Reactant 2

HCID 2206722,5-Dimethylpiperazine, trans-HCID 36531168-chloro-5,10-dihydro-11H-dibenzo[b,e][1,4]diazepin-11-one

Product 1

HCID 136360191HCID 136360191, compoundYield 5.6%

Procedure

8-Chloro-5,10-dihydro-dibenzo[b,e][1,4]diazepine-11-one (25 mg, 0.1 mmol) and trans-2,5-dimethylpiperazine (114 mg, 1.0 mmol) were reacted according to GP4 to give 1.9 mg of the title compound (160FE33A). MS (ESI) 341 (MH+). Purity for MH+ (UV/MS) 100/82.

Sources & evidence

ORD record
ord-3017542d66994bad9c8bc16bbc7f18c3
Source dataset
uspto-grants-2009_06
Patent number
US07550454B2

Reaction notes

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