Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium Azide | HCID 33557 | — |
| Reactant | HCID 68867784 | HCID 68867784 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 86618076 | HCID 86618076 | — |
Reaction Steps
1.5 g of intermediate A1 are stirred into 10 ml N,N-dimethylformamide. 1 g NaN3 is added at room temperature. The mixture is heated up to 60° C. and stirred for 5 hours. 100 ml toluol are added. The organic layer is separated and washed with 3×30 ml water. 90 ml of the solvent are removed. The reaction product precipitates. The crude product is purified by crystallisation from toluol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07550465B2 |
|---|
| Source dataset | uspto-grants-2009_06 |
|---|
| ORD ID | ord-f1d3918729744fd6adbe02b7c675d981 |
|---|
| Source note | uspto-grants-2009_06 |
|---|
