反应详情

温度

60 °C

1.5 g of intermediate A1 are stirred into 10 ml N,N-dimethylformamide. 1 g NaN3 is added at room temperature. The mixture is heated up to 60° C. and stirred for 5 hours. 100 ml toluol are added. The organic layer is separated and washed with 3×30 ml water. 90 ml of the solvent are removed. The reaction product precipitates. The crude product is purified by crystallisation from toluol.

1. customThe organic layer is separated
2. washwashed with 3×30 ml water
3. custom90 ml of the solvent are removed
4. customThe reaction product precipitates
5. customThe crude product is purified by crystallisation from toluol