反应详情

温度

30 °C

2 g of intermediate A1 are suspended in 50 ml ethanol. 1 ml triethylamine and 1 g palladium catalyst are added. An autoclave is used as reaction vessel. Hydrogen is pressed in up to 20 bar pressure. Now, the mixture is stirred at 30° C. for 4 hours. After filtration the solvent is removed. The crude product is dissolved in 100 ml dichloromethane. This solution is washed with 50 ml water. The solvent is removed to isolate pure product.

1. customAn autoclave is used as reaction vessel
2. filtrationAfter filtration the solvent
3. customis removed
4. dissolutionThe crude product is dissolved in 100 ml dichloromethane
5. washThis solution is washed with 50 ml water
6. customThe solvent is removed
7. customto isolate pure product