HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68867784, compound → HCID 68872025, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68867784 | HCID 68867784 | — |
| Reactant | HCID 178418443 | HCID 178418443 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 68872025 | HCID 68872025 | — |
Reaction Steps
7 g of intermediate A1 are suspended in 150 ml tetrahydrofurane. 30 ml of a solution of ethyl magnesium bromide in tetrahydrofurane (3 M) are added. The mixture is stirred for 4 hours at room temperature. After filtration the solvent is removed. The crude product is purified by preparative HPLC.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07550465B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-f9bb50700e274e97a307f5c456aa361e |
| Source note | uspto-grants-2009_06 |