huagongshe.com
HRID1986598

反应详情

EQUATION

反应方程式

HRID 1986598 的结构方程式

REACTANTS

反应物

2
结构：CCCN1CC(C)=C(Cl)C2=C1N1CN(OC)C=C1C=N2
HCID68867784

未命名化合物

结构：CC[Mg]Br
HCID178418443

未命名化合物

PRODUCTS

生成物

1
结构：CCCN1CC(C)=C(CC)C2=C1N1CN(OC)C=C1C=N2
HCID68872025

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

2 次

PROCEDURE

实验过程

7 g of intermediate A1 are suspended in 150 ml tetrahydrofurane. 30 ml of a solution of ethyl magnesium bromide in tetrahydrofurane (3 M) are added. The mixture is stirred for 4 hours at room temperature. After filtration the solvent is removed. The crude product is purified by preparative HPLC.

WORKUP

后处理

  1. filtrationAfter filtration the solvent
  2. customis removed
  3. customThe crude product is purified by preparative HPLC