Ammonia → HCID 68869071, compound

HRID 1986599Notes

Reaction equation

HRID 1986599 reaction equation
Cl[C:2]1[C:7]2[N:8]=[CH:9][C:10]3[N:11]([CH2:12][N:13]([O:15][CH3:16])[CH:14]=3)[C:6]=2[N:5]([CH2:17][CH2:18][CH3:19])[CH2:4][C:3]=1[CH3:20].[NH3:21]>O>[NH2:21][C:2]1[C:7]2[N:8]=[CH:9][C:10]3[N:11]([CH2:12][N:13]([O:15][CH3:16])[CH:14]=3)[C:6]=2[N:5]([CH2:17][CH2:18][CH3:19])[CH2:4][C:3]=1[CH3:20]

Participants

4

Reactant 2

HCID 222AmmoniaHCID 68867784HCID 68867784, compound

Product 1

HCID 68869071HCID 68869071, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Conditions

Temperature
130 °C

Procedure

10 g of intermediate A1 and 200 ml of an aqueous solution of NH3 (32%) are mixed in an autoclave and heated up to 130° C. for 8 hours. The reaction mixture is diluted with 200 ml water. The precipitated reaction product is separated washed with water and dichloro methane and dried at reduced pressure.

Workup

  1. customThe precipitated reaction product
  2. customis separated
  3. washwashed with water and dichloro methane
  4. customdried at reduced pressure

Sources & evidence

ORD record
ord-9f0e81c85b0a4b208f11e51a5293d9ae
Source dataset
uspto-grants-2009_06
Patent number
US07550465B2

Reaction notes

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