Hydrochloric Acid → HCID 68871501, compound

Participants

Reaction Steps

To a solution of 13.52 g of pure 3,4-dimethyl-8-methoxy-1-propyl-imidazo-[1,5-a]-pyrido[3,2-e]-pyrazine and 100 ml of dichloromethane 2.5 equivalents of hydrochloric acid dissolved in 100 ml of water were added. The mixture was vigorously stirred. The dichloromethane layer was then separated and subsequently the water layer was extracted for 6 times with 100 ml dichloromethane. After evaporation of the dichloromethane yellowish crystals remains. (yield 85%; yellowish crystals; m.p. 171-175° C.).

Provenance & Evidence