HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Isobutyl-1-methylxanthine → N7-bromoehtyl 3-isobutyl-1-methylxanthine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Isobutyl-1-methylxanthine | HCID 3758 | — |
| Reactant | 2-Bromoethylamine | HCID 7851 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N7-bromoehtyl 3-isobutyl-1-methylxanthine | HCID 69056164 | — |
Reaction Steps
The process of preparing the compound of formula I comprises the steps of dissolving 3-isobutyl-1-methylxanthine (IBMX) into methanol and stirring with 2-bromoethylamine upon a mantle heater, reacting this mixture with NaOH and then recrystallizing this mixture with methanol to obtain N7-bromoehtyl 3-isobutyl-1-methylxanthine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07550468B2 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-2844dad69a4b4a888264a6e4aab7ae9d |
| Source note | uspto-grants-2009_06 |