化工社化工社 化学情報印刷レポート · 研究参考用
4-Methyl-1,2,3-thiadiazole-5-carbonyl chloride → 4-Methyl-[1,2,3]thiadiazole-5-carboxylic Acid [2-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-benzo[b]thiophen-7-yl]-amide
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | 4-Methyl-1,2,3-thiadiazole-5-carbonyl chloride | HCID 2736982 | — |
| 反応物 | 5-Methoxynicotinic acid | HCID 4738390 | — |
| 反応物 | [2-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-benzo[b]thiophen-7-yl]-nicotinamide | HCID 86590363 | — |
| 生成物 | 4-Methyl-[1,2,3]thiadiazole-5-carboxylic Acid [2-(5-tert-butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-benzo[b]thiophen-7-yl]-amide | HCID 57722421 | 50% |
反応手順
Was prepared as described for -[2-(5-tert-Butyl-3-methanesulfonylamino-2-methoxy-phenylcarbamoyl)-benzo[b]thiophen-7-yl]-nicotinamide starting with 5-methoxy-nicotinic acid to provide 20 mg (50%) of the title compound 4-Methyl-[1,2,3]thiadiazole-5-carbonyl chloride.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US07550461B2 |
| 出典データセット | uspto-grants-2009_06 |
| ORD ID | ord-cfa5c9644a9d45e5b6ed9100b4336125 |
| 出典メモ | uspto-grants-2009_06 |