Hydrochloric Acid → HCID 68851263, compound

Participants

Reaction Steps

In an analogous manner to Example 135, step 4, 1-[1-(3′,4′-dichloro-111′-biphenyl-4-yl)-2-piperazin-1-ylethyl]cyclohexanol dihydrochloride was prepared from tert-butyl 4-[2-(3′,4′-dichloro-1,1′-biphenyl-4-yl)-2-(1-hydroxycyclohexyl)ethyl]piperazine-1-carboxylate. MS (ESI) m/z 433 ([M+H]+); HRMS: calcd for C24H30Cl2N2O.2.00 HCl, 504.1269; found (ESI), 433.1793.

Provenance & Evidence