Sodium Hydroxide → HCID 131727498, compound

Participants

Reaction Steps

To a suspension of 4-[4-chloro-5-(4-ethoxyphenyl)imidazol-1-yl]benzenesulfonamide (1 g, 2.89 mmol) (obtained as described in WO 00/23426) in EtOH (55 mL), NaOH powder (115 mg, 2.89 mmol) was added under argon atmosphere, and the resulting mixture was stirred at room temperature for 2 h. The mixture was concentrated to dryness and a crude product was obtained, which was directly used in the following reaction.

Provenance & Evidence