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HRID19873

反应详情

EQUATION

反应方程式

HRID 19873 的结构方程式

REACTANTS

反应物

2
结构：COc1ncc(B(O)O)cn1
HCID2736778

2-Methoxypyrimidine-5-boronic acid

C5H7BN2O3

结构：CC(C)N1CCC(Oc2ccc3[nH]c(C(=O)N4CCC(F)(F)CC4)cc3c2)CC1
HCID11603838

未命名化合物

2 次

PRODUCTS

生成物

1
结构：COc1ncc(-n2c(C(=O)N3CCC(F)(F)CC3)cc3cc(OC4CCN(C(C)C)CC4)ccc32)cn1
HCID16739593

未命名化合物

PROCEDURE

实验过程

In analogy to the procedure described for the synthesis of example 6, the title compound was synthesized from (4,4-difluoro-piperidin-1-yl)-[5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-methanone (intermediate 1) and 2-methoxy-5-pyrimidineboronic acid. The title compound was obtained in 9% yield as yellow oil. MS (m/e): 514.3 (MH+, 100%).

WORKUP

后处理

  1. customIn analogy to the procedure described for the synthesis of example 6