Midazolam → 8-Chloro-6-(2-fluorophenyl)-1-methyl-5-oxo-4H-5lambda~5~-imidazo[1,5-a][1,4]benzodiazepine
Reaction equation
[CH2:35]([Cl:36])[Cl:37].[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:23]1)[C:7]([c:16]1[c:17]([F:22])[cH:18][cH:19][cH:20][cH:21]1)=[N:8][CH2:9][c:10]1[n:11]-2[c:12]([CH3:15])[n:13][cH:14]1.[Cl:24][c:25]1[cH:26][cH:27][cH:28][c:29]([C:30]([O:31][OH:33])=[O:32])[cH:34]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([cH:23]1)[C:7]([c:16]1[c:17]([F:22])[cH:18][cH:19][cH:20][cH:21]1)=[N+:8]([O-:32])[CH2:9][c:10]1[n:11]-2[c:12]([CH3:15])[n:13][cH:14]1Participants
4
Sources & evidence
- ORD record
- ord-91f5bd569c9c448c97b5d2ec6a1d5807
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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