Acetonitrile → 4-(t-Butylamino)-2-chloro-5-fluoropyrimidine

HRID 198741Notes

Reaction equation

HRID 198741 reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[NH2:14].[CH3:15][C:16]#[N:17].[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:14][C:10]([CH3:11])([CH3:12])[CH3:13])[n:7]1

Participants

4

Reactant 3

HCID 6342AcetonitrileHCID 6385Tert-ButylamineHCID 2507052,4-Dichloro-5-fluoropyrimidine

Product 1

HCID 221212264-(t-Butylamino)-2-chloro-5-fluoropyrimidine

Sources & evidence

ORD record
ord-d6522925119f4155a557f8ffed2253d0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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