Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl 4-isobutyl-1-piperazinecarboxylate → 1-(2-Methylpropyl)piperazine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl 4-isobutyl-1-piperazinecarboxylate | HCID 23069811 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 1-(2-Methylpropyl)piperazine | HCID 2052052 | 112.9% |
반응 단계
The resulting benzyl 4-isobutylpiperazin-1-carboxylate (1.05 g) was dissolved in 35 mL of ethanol, 10% palladium-carbon (750 mg) was added thereto, and the reaction mixture was stirred at room temperature under hydrogen atmosphere (1 atm) for 12 hours. The palladium-carbon was removed by filtration, and the filtrate was evaporated to give the title compound (610 mg) as a colorless oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07550503B2 |
| 출처 데이터셋 | uspto-grants-2009_06 |
| ORD ID | ord-ba36e911f4cd47d39b1bd4e218a2fe6f |
| 출처 메모 | uspto-grants-2009_06 |