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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1987596Generated: November 1, 2026

2-Acetamido-5-aminopyridine → HCID 178466025, compound

https://huagongshe.com/reaction/1987596

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Acetamido-5-aminopyridineHCID 2735219—
ReactantHCID 178434119HCID 178434119—
SolventEthanolHCID 702—
ProductHCID 178466025HCID 178466025—

Reaction Conditions

Temperature180 °C

Reaction Steps

(Z)-4-(4-chloroquinolin-2(1H)-ylidene)-3-methyl-1H-pyrazol-5(4H)-one (0.033 g, 0.13 mmol) and 2-acetamido-5-aminopyridine (Matrix) (0.058 g, 0.38 mmol) were dissolved in ethanol (1.5 mL). The reaction mixture was heated to 180° C. using a microwave reactor for 6 hrs. The mixture was concentrated and purified by LC-MS to give the title compounds of Example 4 and Example 5.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07550598B2
Source datasetuspto-grants-2009_06
ORD IDord-d8d59679e9c241b99da44f5d531574ac
Source noteuspto-grants-2009_06