反应详情

The tile compound was synthesized using N-(4-((5-oxo-4,5-dihydro-1H-pyrazol-3-yl)methyl)phenyl)methanesulfonamide and quinoline N-oxide in acetic anhydride according to the procedure described in Example 23. The N-(4-((5-oxo-4,5-dihydro-1H-pyrazol-3-yl)methyl)phenyl)methanesulfonamide was synthesized using 2-(4-(methylsulfonamido)phenyl)acetic acid and Meldrum's acid. 1H NMR (400 MHz, DMSO-d6) δ ppm 2.91 (s, 3H) 4.08 (s, 1H) 4.43 (s, 1H) 7.10 (d, J=3.79 Hz, 2H) 7.24-7.37 (m, 2H) 7.46 (d, J=6.06 Hz, 1H) 7.67-7.77 (m, 2H) 7.82-7.94 (m, 2H) 8.17-8.29 (m, 1H) 9.60 (s, 1H) 11.40 (s, 1H); ESI-MS: m/z calc'd for C20H18N4O3S 394.45. found 395.3 (M+H)+.

1. customThe tile compound was synthesized