Quinoline 1-oxide → HCID 178518890, compound

HRID 1987639Notes

Reaction equation

HRID 1987639 reaction equation
[C:1]1([C:7]2[CH2:11][C:10](=[O:12])[NH:9][N:8]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[N+:13]1([O-])[C:22]2[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH:16]=[CH:15][CH:14]=1>>[C:1]1([C:7]2=[N:8][NH:9][C:10](=[O:12])/[C:11]/2=[C:14]2\[NH:13][C:22]3[C:17]([CH:16]=[CH:15]\2)=[CH:18][CH:19]=[CH:20][CH:21]=3)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

3

Reactant 2

HCID 15366Quinoline 1-oxideHCID 785775-Phenyl-4H-pyrazol-3-ol

Product 1

HCID 178518890HCID 178518890, compound

Procedure

The title compound was synthesized using 3-phenyl-1H-pyrazol-5(4H)-one and quinoline N-oxide according to the procedure described in Example 23. 1H NMR (400 MHz, DMSO-d6) 8 ppm 7.21 (d, J=9.09 Hz, 1H) 7.50-7.60 (m, 7H) 7.82 (t, J=7.71 Hz, 1H) 7.93 (t, J=6.82 Hz, 2H) 8.33 (d, J=8.84 Hz, 1H); ESI-MS: m/z calc'd for C18H13N3O 287.32. found 288.3 (M+H)+.

Sources & evidence

ORD record
ord-1e1a41a0815c4fe8b16bf0221665cc0c
Source dataset
uspto-grants-2009_06
Patent number
US07550598B2

Reaction notes

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