HRID1987845

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID5356259

2-Butenoic acid, phenylmethyl ester, (2E)-

C11H12O2

结构：CCOC(=O)Nc1cc[n+](CC(=O)c2ccc([N+](=O)[O-])c(OC)c2)cc1.[Br-]

HCID86607555

未命名化合物

PRODUCTS

生成物

结构：CCOC(=O)Nc1ccn2c(C(=O)c3ccc([N+](=O)[O-])c(OC)c3)c(C)c(C(=O)OCc3ccccc3)c2c1

HCID86607557

未命名化合物

收率 26%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID160959

Manganous oxide

MnO

PROCEDURE

实验过程

This compound is prepared according to the same method as that described in Example 47 Step B from 1.8 g (4.1 mmol) of 4-[N-(ethoxycarbonyl)amino]-1-[2-(3-methoxy-4-nitrophenyl)-2-oxoethyl]pyridinium bromide with benzyl crotonate in the presence of manganese oxide as oxidizing agent. 573 mg of a yellow powder are obtained.

WORKUP

后处理

customThis compound is prepared

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-d5ad3b8667ee4e1cb3475e35f2fcbae8
来源数据集: uspto-grants-2009_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07553845B2
来源说明: uspto-grants-2009_06

反应 SMILES

[Br-].[CH2:2]([O:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][N+:11]([CH2:14][C:15]([C:17]2[CH:22]=[CH:21][C:20]([N+:23]([O-:25])=[O:24])=[C:19]([O:26][CH3:27])[CH:18]=2)=[O:16])=[CH:10][CH:9]=1)=[O:6])[CH3:3].[C:28]([O:33][CH2:34][C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1)(=[O:32])/[CH:29]=[CH:30]/[CH3:31]>[O-2].[Mn+2]>[CH2:2]([O:4][C:5]([NH:7][C:8]1[CH:13]=[CH:12][N:11]2[C:10]([CH:9]=1)=[C:29]([C:28]([O:33][CH2:34][C:35]1[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=1)=[O:32])[C:30]([CH3:31])=[C:14]2[C:15](=[O:16])[C:17]1[CH:22]=[CH:21][C:20]([N+:23]([O-:25])=[O:24])=[C:19]([O:26][CH3:27])[CH:18]=1)=[O:6])[CH3:3]