反应详情

3-Bromo-xanthen-9-one (0.25 g, 0.9 mmol), 2-acetamidophenylboronic acid (0.99 mmol), 1,1′-bis-(diphenylphosphino)ferrocene-palladium (II) dichloride (33 mg, 0.045 mmol), cesium carbonate (0.59 g, 1.8 mmol), dioxane (4 mL), and ethanol (2 mL) were microwaved in a 5-mL reaction vessel at 100° C. for 5 min. The reaction was filtered and concentrated. The residue was purified by reverse phase chromatography to afford N-[2-(9-Oxo-9H-xanthen-3-yl)-phenyl]-acetamide.

1. filtrationThe reaction was filtered
2. concentrationconcentrated
3. customThe residue was purified by reverse phase chromatography