Benzaldehyde → HCID 178518081, compound

HRID 1987955Notes

Reaction equation

HRID 1987955 reaction equation
[CH:1](=O)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[CH2:9]([N+:16]#[C-:17])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1.[O-:18][C:19]#[N:20].[K+].[NH2:22][C:23]1[CH:28]=[CH:27][C:26]([C:29]([F:32])([F:31])[F:30])=[CH:25][CH:24]=1.[NH+]1C=CC=CC=1>>[CH2:9]([NH:16][C:17]1[CH:1]([C:2]2[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=2)[N:22]([C:23]2[CH:28]=[CH:27][C:26]([C:29]([F:30])([F:31])[F:32])=[CH:25][CH:24]=2)[C:19](=[O:18])[N:20]=1)[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

6

Reactant 5

HCID 240BenzaldehydeHCID 99644-(Trifluoromethyl)anilineHCID 82558Benzyl isocyanideHCID 4989215PyridiniumHCID 11378442Potassium cyanate

Product 1

HCID 178518081HCID 178518081, compoundYield 51%

Procedure

Prepared in analogy to example 1 from benzaldehyde, benzylisocyanide, potassium cyanate, 4-aminobenzotrifluoride and pyridinium hydrochlorideas a light brown solid. Yield=51%. MS (m/e): 410.3 (100%; M+H+), 432.3 (21%; M+Na).

Sources & evidence

ORD record
ord-e870bb6004c84b6d973adbfbc19788fe
Source dataset
uspto-grants-2009_06
Patent number
US07553862B2

Reaction notes

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