HuagongsheHuagongshe Chemistry Print Report · For research reference only
Z-N-Me-Val-N-Me-Tyr(3-t-Bu)-NHSO2Me → N-Me-Val-N-Me-Tyr(3-t-Bu)-NHSO2Me
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Z-N-Me-Val-N-Me-Tyr(3-t-Bu)-NHSO2Me | HCID 131727506 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | N-Me-Val-N-Me-Tyr(3-t-Bu)-NHSO2Me | HCID 131727508 | 100.2% |
Reaction Steps
A mixture of Z-N-Me-Val-N-Me-Tyr(3-t-Bu)-NHSO2Me (0.65 g, 1.13 mmol) and 20% palladium hydroxide/carbon (0.09 g) in methanol (10 ml) was stirred at room temperature for 2.5 hours in a hydrogen atmosphere. The reaction mixture was filtered and the filtrate was evaporated to remove the solvent under reduced pressure, giving crude N-Me-Val-N-Me-Tyr(3-t-Bu)-NHSO2Me (0.50 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07553969B1 |
| Source dataset | uspto-grants-2009_06 |
| ORD ID | ord-ddfcd71dfe69498085251f916009fb6f |
| Source note | uspto-grants-2009_06 |