反应详情

A suspension of N-benzyl-2-(4-benzyloxy-3-tert-butylphenyl)-1-methyl-N-(benzyloxycarbonyl)-ethylamine (2.35 g, 4.50 mmol) and 20% palladium hydroxide/carbon catalyst (0.50 g) in methanol (30 ml) was stirred in a hydrogen atmosphere overnight. The mixture was filtered to remove the catalyst and the filtrate was evaporated to remove the solvent under reduced pressure, giving 2-(3-tert-butyl-4-hydroxyphenyl)-1-methylethylamine (T21) (0.90 g, 96%).

1. filtrationThe mixture was filtered
2. customto remove the catalyst
3. customthe filtrate was evaporated
4. customto remove the solvent under reduced pressure