Stearyl Alcohol → HCID 17957563, compound

HRID 1988515Notes

Reaction equation

HRID 1988515 reaction equation
[F:1][C:2]([F:15])([F:14])[C:3]([NH:5][CH2:6][CH:7]1[CH2:11][O:10][CH:9]([O:12][CH3:13])[O:8]1)=[O:4].[CH2:16](O)[CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]C.C1(C)C=CC(S([O-])(=O)=O)=CC=1.[NH+]1C=CC=CC=1>C1CCCCC1>[F:15][C:2]([F:14])([F:1])[C:3]([NH:5][CH2:6][CH:7]1[CH2:11][O:10][CH:9]([O:12][CH2:13][CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH3:16])[O:8]1)=[O:4]

Participants

5

Reactant 3

HCID 8221Stearyl AlcoholHCID 466102Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1)HCID 17957558HCID 17957558, compound

Product 1

HCID 17957563HCID 17957563, compound

Reagents, catalysts & solvents 1

HCID 8078CyclohexaneSolvent

Procedure

3 g of 2,2,2-trifluoro-N-(2-methoxy-[1,3]dioxolan-4-ylmethyl)acetamide (Ortho 1, 13.09 mmol) were mixed with 3.54 g of octadecanol (13.09 mmol). The mixture was melted at 80° C. and left for 2 hours after the addition of 32 mg of pyridinium para-toluenesulfonate (0.13 mmol). The crude reaction product was then dissolved in cyclohexane, washed with a saturated sodium hydrogen carbonate solution and then with a saturated sodium chloride solution, dried over magnesium. sulfate and then concentrated to dryness. This crude product was used as it was for the next step.

Workup

  1. customThe crude reaction product
  2. washwashed with a saturated sodium hydrogen carbonate solution
  3. dry with materialwith a saturated sodium chloride solution, dried over magnesium
  4. concentrationsulfate and then concentrated to dryness

Sources & evidence

ORD record
ord-b8dd7a59e3664098aec2facfbec18648
Source dataset
uspto-grants-2010_01
Patent number
US07641914B2

Reaction notes

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