Pyrrolidine → (1-Phenylcyclopropyl)(pyrrolidin-1-yl)methanone

HRID 1988611Notes

Reaction equation

[C:1]1([C:7]2([C:10]([OH:12])=O)[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[NH:13]1[CH2:17][CH2:16][CH2:15][CH2:14]1>>[C:1]1([C:7]2([C:10]([N:13]3[CH2:17][CH2:16][CH2:15][CH2:14]3)=[O:12])[CH2:8][CH2:9]2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

Reactant 2

HCID 31268Pyrrolidine

HCID 802061-Phenylcyclopropanecarboxylic acid

Product 1

HCID 57762795(1-Phenylcyclopropyl)(pyrrolidin-1-yl)methanone

Procedure

The title compound was prepared from 1-phenylcyclopropanecarboxylic acid and pyrrolidine using a similar procedure to that described for Description 8.

Sources & evidence

ORD record: ord-44610d30db2f4c3da3af1da7fc118f70
Source dataset: uspto-grants-2010_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07642256B2

Reaction notes

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