4-Chlorobenzyl alcohol → 4-[(4-Chlorophenyl)methoxy]-3-nitropyridine

HRID 1988838Notes

Reaction equation

HRID 1988838 reaction equation
Cl[C:2]1[CH:7]=[CH:6][N:5]=[CH:4][C:3]=1[N+:8]([O-:10])=[O:9].[Cl:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16][OH:17])=[CH:14][CH:13]=1>>[Cl:11][C:12]1[CH:19]=[CH:18][C:15]([CH2:16][O:17][C:2]2[CH:7]=[CH:6][N:5]=[CH:4][C:3]=2[N+:8]([O-:10])=[O:9])=[CH:14][CH:13]=1

Participants

3

Reactant 2

HCID 133974-Chlorobenzyl alcoholHCID 27357814-Chloro-3-nitropyridine

Product 1

HCID 687003244-[(4-Chlorophenyl)methoxy]-3-nitropyridineYield 78%

Procedure

In accordance with the same procedures as in Preparation 2, except for using 4-chloro-3-nitropyridine prepared in Step 1 of Preparation 1 and 4-chlorobenzyl alcohol, the titled compound was obtained as a white solid. (Yield: 78.0%)

Workup

  1. customIn accordance with the same procedures as in Preparation 2

Sources & evidence

ORD record
ord-0e2bd51a65b94b20b9d409262b107226
Source dataset
uspto-grants-2010_01
Patent number
US07642269B2

Reaction notes

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