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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1988848Generated: October 26, 2026

4-(Trifluoromethyl)benzenemethanol → 3-Nitro-4-{[4-(trifluoromethyl)phenyl]methoxy}pyridine

https://huagongshe.com/reaction/1988848

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzenemethanolHCID 67684—
Reactant4-Chloro-3-nitropyridineHCID 2735781—
Product3-Nitro-4-{[4-(trifluoromethyl)phenyl]methoxy}pyridineHCID 6870643189.5%

Reaction Steps

In accordance with the same procedures as in Preparation 2, except for using 4-chloro-3-nitropyridine prepared in Step 1 of Preparation 1 and 4-trifluoromethylbenzyl alcohol, the titled compound was obtained as a yellow solid. (Yield: 89.5%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07642269B2
Source datasetuspto-grants-2010_01
ORD IDord-09b6b3d025c3449f9d3634eddb89acd4
Source noteuspto-grants-2010_01