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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1988950Generated: October 29, 2026

4-Methoxybenzylamine → N-Cyclopropyl-3-fluoro-4-methyl-5-{1-[2-({[4-(methyloxy)phenyl]methyl}amino)-2-oxoethyl]-1H-indazol-5-yl}benzamide

https://huagongshe.com/reaction/1988950

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxybenzylamineHCID 75452—
ReactantHCID 58656520HCID 58656520—
ProductN-Cyclopropyl-3-fluoro-4-methyl-5-{1-[2-({[4-(methyloxy)phenyl]methyl}amino)-2-oxoethyl]-1H-indazol-5-yl}benzamideHCID 58656502—

Reaction Steps

Example 134 was prepared by General Method D using methyl (5-{5-[(cyclopropylamino)carbonyl]-3-fluoro-2-methylphenyl}-1H-indazol-1-yl)acetate (Example 123) and 4-methoxybenzylamine to give the title compound (0.012 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07642276B2
Source datasetuspto-grants-2010_01
ORD IDord-b2ba7ed331294e4c9393bf4b361de3fe
Source noteuspto-grants-2010_01