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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1988953Generated: November 4, 2026

Cyclopropanemethanamine → N-cyclopropyl-3-(1-{2-[(cyclopropylmethyl)amino]-2-oxoethyl}-1H-indazol-5-yl)-5-fluoro-4-methylbenzamide

https://huagongshe.com/reaction/1988953

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCyclopropanemethanamineHCID 75646—
ReactantHCID 58656520HCID 58656520—
ProductN-cyclopropyl-3-(1-{2-[(cyclopropylmethyl)amino]-2-oxoethyl}-1H-indazol-5-yl)-5-fluoro-4-methylbenzamideHCID 58656451—

Reaction Steps

Example 137 was prepared by General Method D using methyl (5-{5-[(cyclopropylamino)carbonyl]-3-fluoro-2-methylphenyl}-1H-indazol-1-yl)acetate (Example 123) and 1-cyclopropylmethanamine to give the title compound (0.008 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07642276B2
Source datasetuspto-grants-2010_01
ORD IDord-9ca721f97cb2465b85c0c0aa3ce9b073
Source noteuspto-grants-2010_01