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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1988993Generated: November 1, 2026

Hydrochloric Acid → HCID 178519448, compound

https://huagongshe.com/reaction/1988993

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantWaterHCID 962—
Reactant1,4-DioxaneHCID 31275—
ReactantIndole-4-carboxaldehydeHCID 333703—
ReactantSodium NitriteHCID 23668193—
ProductHCID 178519448HCID 178519448—

Reaction Steps

The commercially available 1H-indole-4-carbaldehyde is reacted with NaNO2 in the presence of HCl and H2O in dioxane to produce the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07642278B2
Source datasetuspto-grants-2010_01
ORD IDord-af522c89942f45ff827b738ec39d8c6a
Source noteuspto-grants-2010_01