Hydrochloric Acid → HCID 178519448, compound

HRID 1988993Notes

Reaction equation

HRID 1988993 reaction equation
[NH:1]1[C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([CH:10]=[O:11])[C:4]=2C=C1.[N:12]([O-])=O.[Na+].Cl.O.[O:18]1[CH2:23][CH2:22]OCC1>>[NH:1]1[C:9]2[CH:8]=[CH:7][CH:6]=[C:5]([CH:10]=[O:11])[C:4]=2[C:22]([CH:23]=[O:18])=[N:12]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 962WaterHCID 312751,4-DioxaneHCID 333703Indole-4-carboxaldehydeHCID 23668193Sodium Nitrite

Product 1

HCID 178519448HCID 178519448, compound

Procedure

The commercially available 1H-indole-4-carbaldehyde is reacted with NaNO2 in the presence of HCl and H2O in dioxane to produce the title compound.

Sources & evidence

ORD record
ord-af522c89942f45ff827b738ec39d8c6a
Source dataset
uspto-grants-2010_01
Patent number
US07642278B2

Reaction notes

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